That being said, we want to point out that these side effects are not common. WebBut can collagen cause headaches? WebMD does not provide medical advice, diagnosis or treatment. A small study of 53 men revealed the positive effects of taking collagen supplements when exercising. The effect of oral collagen peptide supplementation on skin moisture and the dermal collagen network: evidence from an ex vivo model and randomized, placebo-controlled clinical trials. The Bone Biomarker Response to an Acute Bout of Exercise: A Systematic Review with Meta-Analysis. Heart failure: Could a low sodium diet sometimes do more harm than good? Collagen peptides powder may also cause headaches, dizziness, or lightheadedness in some users. The https:// ensures that you are connecting to the This information may not fit your specific health circumstances. Oliviero F, Ramonda R, Hoxha A, et al. Marine collagen supplements. 8600 Rockville Pike There is some evidence to suggest that collagen supplements can help with restoring or preventing the deterioration of the cartilage in the joints. After those 8 weeks, the women who took the supplement had higher elasticity and moisture levels. The site is secure. Effect of calcium and vitamin D supplementation with and without collagen peptides on bone turnover in postmenopausal women with osteopenia. An official website of the United States government. Reumatismo. Learn about some top options here. Be sure to choose a collagen peptide product that best suits your needs and goals. Molecules 2021;26(16):4880. View abstract. Would you like email updates of new search results? Oral intake of specific bioactive collagen peptides reduces skin wrinkles and increases dermal matrix synthesis. CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. * "It What is the latest research on the form of cancer Jimmy Carter has? Proksch E, Schunck M, Zague V, Segger D, Degwert J, Oesser S. Oral intake of specific bioactive collagen peptides reduces skin wrinkles and increases dermal matrix synthesis. Please enable it to take advantage of the complete set of features! The review also showed that it helped reduce joint pain. View abstract. From arthritis, to skin health, to post surgery healing, a quality collagen supplement can do wonders for your body. View abstract. doi: 10.1042/BSR20181347. Camilion JV, Khanna S, Anasseri S, Laney C, Mayrovitz HN. If you have allergies, make sure to purchase supplements that arent made from collagen sources youre sensitive to. However, more research is necessary to prove the effects of collagen in supporting heart health. Having, high levels of calcium in your blood is also known as hypercalcemia, and seems to be more predominantly an issue in women., Whether collagen can cause headaches or not is a great question to be asking, especially when trying to decide which supplements are right for you and your body. 2015;95(4):702-7. 2016;2016:4389410. The .gov means its official. Adv Skin Wound Care. Federal government websites often end in .gov or .mil. Bauza E, Oberto G, Berghi A, Dal CF, Domloge N. Collagen-like peptide exhibits a remarkable antiwrinkle effect on the skin when topically applied: in vivo study. Migraine pain-relay centers, including the trigeminal ganglion, trigeminal nucleus caudalis, and thalamus, contain glutamate-positive neurons, and glutamate activates the trigeminal nucleus caudalis. J Sci Food Agric. Rahimi MD, Hassani P, Kheirkhah MT, Fadardi JS. Rheumatoid arthritis, lupus, dermatomyositis and scleroderma are autoimmune, connective tissue diseases known to damage collagen. Curr Med Res Opin. 2018;10(7).View abstract. Miyanaga M, Uchiyama T, Motoyama A, Ochiai N, Ueda O, Ogo M. Oral Supplementation of Collagen Peptides Improves Skin Hydration by Increasing the Natural Moisturizing Factor Content in the Stratum Corneum: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial. Speak with a, Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Bird Flu Deaths Prompt U.S. to Test Vaccine in Poultry, COVID Treatment in Development Appears Promising, Marriage May Help Keep Your Blood Sugar in Check, Getting Outdoors Might Help You Take Fewer Meds, New Book: Take Control of Your Heart Disease Risk, Getting Help for a Loved One With Psychosis: It's Complicated, Health News and Information, Delivered to Your Inbox, Osteoarthritis. Rheumatoid arthritis, lupus, dermatomyositis and scleroderma are autoimmune, connective tissue diseases known to damage collagen. ProT Powder Collagen Protein - 32 Servings. Health Canada. Also, in many cases, the collagen is hydrolyzed. 2009;60 Suppl 2:99-113. Kynurenines and PACAP in Migraine: Medicinal Chemistry and Pathogenetic Aspects. Collagen supplements may help support skin, hair, and joint health. Apweiler E, Wallace D, Stansfield S, Allerton DM, Brown MA, Stevenson EJ, Clifford T. Sports (Basel). Elam ML, Johnson SA, Hooshmand S, et al. Oral collagen supplementation for skin aging: A fad or the future? Your body makes collagen naturally, but you can also consume it through collagen supplements This group saw a significant reduction in artery stiffness and a reduction in their low-density lipoprotein, or bad, cholesterol levels. Alipoor E, Hosseinzadeh-Attar MJ, Salehi S, et al. Given that glutamic acid is one of the amino acids present in the collagen protein, eating too many collagen peptides may indirectly lead to an unwanted headache. Creams have the advantage of providing extra hydration, making them particularly suitable for dry, wrinkled, or aging skin, and they pose even fewer risks than the already rare potential side effects of oral supplements. Hydroxyproline ingestion and urinary oxalate and glycolate excretion. In the cosmetic industry, marine collagen is one of the most popular types, as it causes less inflammation than animal sources and is less likely to contain Collagen is a protein that our body already produces, so when taking it in a supplement form, you are replenishing your collagen stores with animal-based collagen., Since it is something that your body already recognizes and needs, the risk is relatively minimal and there are few health concerns about how collagen reacts within your body., Now, this isnt to say that there are no side effects, allergy concerns, or risks involved in taking a collagen supplement., Introducing any new supplement into your diet should be done so with the consultation of a medical professional, especially if you are taking prescription medications, are pregnant, or have any underlying health conditions., Every person taking a supplement may have a different reaction when introducing it into their diet. View abstract. Bookshelf So as you see, collagen can cause headaches and other issues in some people. Collagen benefits for skin and hair.*. National Library of Medicine As a person ages and collagen production slows, bones can become weaker as the person loses the collagen necessary to keep the bones strong and supported. Would you like email updates of new search results? Dressler P, Gehring D, Zdzieblik D, Oesser S, Gollhofer A, Knig D. Improvement of Functional Ankle Properties Following Supplementation with Specific Collagen Peptides in Athletes with Chronic Ankle Instability. Glutamate and Its Receptors as Therapeutic Targets for Migraine. Bone turnover; Collagen; Exercise recovery; Hydrolyzed collagen; Inflammation; Muscle soreness. View abstract. It is responsible for several biological functions, one of which is to provide structural support in connective tissue, muscle, and skin. 2018;13(4):438-52. Cannabis Addiction and the Brain: a Review. Here are the 10 Best Fruits That Will Make You Poop better. HHS Vulnerability Disclosure. anti-aging; collagen peptides; fragmentation; glycosaminoglycan; hyaluronic acid; reflectance confocal microscopy. Collagen supplements are available in the form of tablets, capsules, and powders. View abstract. A person can also use collagen supplements while following a keto diet plan. 2021;20(1):188-194. 2004;26(3-4):105-11. Nutrients. View abstract. Theres currently 80 approved peptide drugs worldwide. Biol Pharm Bull. Effects of protein supplements on muscle damage, soreness and recovery of muscle function and physical performance: a systematic review. Moskowitz RW. Am J Med Sci. Undergoing the hydrolyzation process makes collagen easier for the body to absorb. When applied topically or ingested, products containing collagen peptides signal to your body that it needs to produce more collagen. Skin rashes. and transmitted securely. J Sci Food Agric. Borumand, M., & Sibilla, S. (2015). These chemical ingredients can cause systemic inflammation as well as accumulate within the body, leading to enlarged and clogged pores, and ultimately more breakouts. View abstract. Mar Drugs. Maximal isometric voluntary contractions, countermovement jumps (CMJ), muscle soreness (200 mm visual analogue scale), pressure pain threshold, Brief Assessment of Mood Adapted (BAM +) and a range of blood markers associated with muscle damage, inflammation and bone turnover C-terminal telopeptide of type 1 collagen (-CTX) and N-terminal propeptides of type 1 pro-collagen (P1NP) were measured before supplementation (baseline; BL), pre, post, 1.5, 24 and 48 h post-exercise. Choi SY, Kim WG, Ko EJ, et al. Specific Collagen Peptides Improve Bone Mineral Density and Bone Markers in Postmenopausal Women-A Randomized Controlled Study. Looking at the ingredients we find, they are natural, gluten-free, non-GMO, dairy-free, grass-fed pasture-raised cows, and wild-caught fish, and cage-free chickens. Oikawa SY, Kamal MJ, Webb EK, McGlory C, Baker SK, Phillips SM. When it comes to skin care, collagen peptides are most often used to improve skin smoothness, firmness and moisture. WebCollagen peptides are used as a bioactive ingredient in nutricosmetic products and have been shown in preclinical studies to improve skin barrier function, to induce the synthesis of collagen and hyaluronic acid, and to promote fibroblast growth and migration. The vegan options may not be available everywhere, but many are available online. Oral Intake of Low-Molecular-Weight Collagen Peptide Improves Hydration, Elasticity, and Wrinkling in Human Skin: A Randomized, Double-Blind, Placebo-Controlled Study. The https:// ensures that you are connecting to the For more in-depth resources about vitamins, minerals, and supplements, visit our dedicated hub. View abstract. 2018;10(1). Others may experience side effects causing issues with the skin or digestive system, among other problems, but the likelihood of this is based largely on the quality of your chosen collagen peptides product. Protein and Sport: Alternative Sources and Strategies for Bioactive and Sustainable Sports Nutrition. Li X, He Z, Xu J, Su C, Xiao X, Zhang L, Zhang H, Li H. Foods. WebAutoimmune diseases (your bodys immune system attacks its own tissue) can damage collagen. We do not provide medical diagnosis, advice, or treatments. Efficacy and Safety of Topical or Oral Hydrolyzed Collagen in Women with Dermatoporosis: A Randomized, Double-Blind, Factorial Design Study. doi: 10.1097/MD.0000000000014099. Many believe that collagen supplements can help reduce the effects of aging, such as by adding moisture to the skin, reducing wrinkles, and improving elasticity. It also plays a role in joint and bone health. This site needs JavaScript to work properly. Most collagen users do not experience any adverse effects when taking a high-quality collagen supplement at the proper dosage. We include products we think are useful for our readers. pii: E97. Collagen peptides are used as a bioactive ingredient in nutricosmetic products and have been shown in preclinical studies to improve skin barrier function, to induce the synthesis of collagen and hyaluronic acid, and to promote fibroblast growth and migration. Ex vivo experiments demonstrated that collagen peptides induce collagen as well as glycosaminoglycan production, offering a mechanistic explanation for the observed clinical effects. An official website of the United States government. National Library of Medicine Nutrients 2018;10(10). They accomplish this by stimulating new collagen growth, in turn reducing wrinkles, boosting skin elasticity, and improving skin hydration. Topical application and oral supplementation of peptides in the improvement of skin viscoelasticity and density. However, some of the potential health benefits of collagen supplements include: Some people who take collagen supplements are looking to improve the look and overall health of their skin. WebThis study examined whether consuming collagen peptides (CP) before and after strenuous exercise alters markers of muscle damage, inflammation and bone turnover. Jendricke P, Kohl J, Centner C, Gollhofer A, Knig D. Influence of specific collagen peptides and concurrent training on cardiometabolic parameters and performance indices in women: A randomized controlled trial. Treatment with marine collagen peptides modulates glucose and lipid metabolism in Chinese patients with type 2 diabetes mellitus. Effects of collagen peptides on recovery following eccentric exercise in resistance-trained males-A pilot study. (2016). Licensed Natural Health Products Database. Additionally, collagen contains various animal proteins, which can cause allergic reactions in some people. The participants engaged in regular exercise for 12 weeks. If you have a history of calcium oxalate kidney stones, exercise caution when incorporating collagen peptides by beginning with no more than about 1 tablespoon per day, and always stay well-hydrated. Testing the Role of Glutamate NMDA Receptors in Peripheral Trigeminal Nociception Implicated in Migraine Pain. Zdzieblik D, Oesser S, Baumstark MW, Gollhofer A, Knig D. Collagen peptide supplementation in combination with resistance training improves body composition and increases muscle strength in elderly sarcopenic men: a randomised controlled trial. These include: Collagen peptide supplements can offer a range of benefits from improved skin health to a reduction in joint pain and stronger hair and nails. The protein collagen has 3 essential amino acids that decrease constipation, helps with leaky gut syndrome, and even reduces diarrhea. However, its important to ensure you do not have allergies or sensitivities to collagen and that you select a quality product in order to avoid unnecessary side effects. Proksch E, Schunck M, Zague V, Segger D, Degwert J, Oesser S. Skin Pharmacol Physiol. Int J Sport Nutr Exerc Metab 2021. Medical News Today only shows you brands and products that we stand behind. Unfortunately, experts say that the research supporting all of these claims is limited. The question that often arises in the minds of people before consuming it is, Can collagen cause diarrhea? The answer to this As with any supplement, collagen supplements do have some potential side effects, especially when taken in excess. We currently have no information for COLLAGEN PEPTIDES overview. View abstract. View abstract. Tak YJ, Kim YJ, Lee JG, et al. Praet SFE, Purdam CR, Welvaert M, et al. But these supplements are also touted to support digestion and heart health, prevent bone loss and increase muscle mass. Its always something View abstract. Epub 2022 Dec 22. 2019 Jan;98(3):e14099. Its always best to speak with your doctor when beginning to take new supplements, particularly in order to avoid adverse interactions with medications. 2015;14(4):291-301. This is typically due to Sibilla S, Godfrey M, Brewer S, Budh-Raja A, Genovese L. An overview of the beneficial effects of hydrolysed collagen as a nutraceutical on skin properties: Scientific background and clinical studies. In a small study of 30 participants, half took 16 g of collagen tripeptide for 6 months. Some other potential things that collagen may help with include: Collagen supplements come in a variety of types. Zhu CF, Li GZ, Peng HB, Zhang F, Chen Y, Li Y. 2012;60(16):4096-4101. Mohammed A, He S. A Double-Blind, Randomized, Placebo-Controlled Trial to Evaluate the Efficacy of a Hydrolyzed Chicken Collagen Type II Supplement in Alleviating Joint Discomfort. View abstract. Dolan E, Dumas A, Keane KM, Bestetti G, Freitas LHM, Gualano B, Kohrt WM, Kelley GA, Pereira RMR, Sale C, Swinton PA. Sports Med. Effectiveness of eye movement exercise and diaphragmatic breathing with jogging in reducing migraine symptoms: A preliminary, randomized comparison trial. 2022 Nov 25;14(23):5027. doi: 10.3390/nu14235027. Aguirre A, Gil-Quintana E, Fenaux M, Erdozain S, Sarria I. J Diet Suppl. WebYes, collagen does make you poop more! Subscribe to get special offers, free giveaways, and once-in-a-lifetime deals. This study examined whether consuming collagen peptides (CP) before and after strenuous exercise alters markers of muscle damage, inflammation and bone turnover. Unable to load your collection due to an error, Unable to load your delegates due to an error. Clifford T, Bell O, West DJ, Howatson G, Stevenson EJ. View abstract. Sugihara F, Inoue N, Venkateswarathirukumara S. Ingestion of bioactive collagen hydrolysates enhanced pressure ulcer healing in a randomized double-blind placebo-controlled clinical study. doi: 10.7759/cureus.27666. Effect of the novel low molecular weight hydrolyzed chicken sternal cartilage extract, BioCell Collagen, on improving osteoarthritis-related symptoms: a randomized, double-blind, placebo-controlled trial. The animal ingredients commonly found in collagen peptide supplements can be extraordinarily high in calcium, which, in come cases can lead to hypercalcemia. Similar to vegan options, a person may want to look for a collagen supplement that specifically aims to support the keto diet. Please enable it to take advantage of the complete set of features! Although certain foods, such as bone broth, contain collagen, people who want wrinkle-free skin or other health benefits often look to supplements to increase their collagen intake. government site. Careers. 5. 2014;27(3):113-9. Zhu CF, Li GZ, Peng HB, Zhang F, Chen Y, Li Y. Most collagen users do not experience any adverse effects when taking a high-quality collagen supplement at the proper dosage., The source of the collagen is also a huge factor in whether or not collagen can cause headaches and other side effects., For instance, many bone broth based collagen supplements are very high in sodium and potassium, not to mention the collagen in that type of supplement is harder to digest.. Zdzieblik D, Jendricke P, Oesser S, Gollhofer A, Knig D. The Influence of Specific Bioactive Collagen Peptides on Body Composition and Muscle Strength in Middle-Aged, Untrained Men: A Randomized Controlled Trial. Burns. WebCollagen comprises about 60% of cartilage, a very firm tissue that surrounds bones and cushions them from the shock of high-impact movements; so a breakdown in collagen could lead to a loss of cartilage and joint problems. One review of the research into collagen supplementation found that using hydrolyzed collagen supplements helps promote joint health and potentially restore some bone density in people with osteoporosis and osteoarthritis. 2019;11(4). The .gov means its official. View abstract. 2017;88(3):357-364. A 2016 animal study also found that collagen hydrolysate (also called collagen peptides) reduced fat cell size and weight gain in rats. Allergic Reaction. Pressure ulcer healing with a concentrated, fortified, collagen protein hydrolysate supplement: a randomized controlled trial. Scientists describe collagenous colitis as a type of microscopic colitis because the inflammation it causes is only noticeable under a microscope. Nutrients 2021;13(7):2454. You can learn more about how we ensure our content is accurate and current by reading our. Though this study is promising, more research is necessary to fully determine the positive effects that collagen may have on muscle growth. Taking collagen peptides by mouth might slightly relieve pain and improve joint function in people with. In particular, the spongy cartilage of the joints starts to wear away. HIGH CHOLESTEROL on Keto Diet (My 4-Year High Fat Diet Results!) Collagen supplementation as a complementary therapy for the prevention and treatment of osteoporosis and osteoarthritis: A systematic review. Can poor sleep impact your weight loss goals? It can cause allergic reactions. Kalman DS, Schwartz HI, Pachon J, Sheldon E, Almada AL. Pre-Bed Casein Protein Supplementation Does Not Enhance Acute Functional Recovery in Physically Active Males and Females When Exercise is Performed in the Morning. 2022 Aug 4;14(8):e27666. Effect of collagen hydrolysate in articular pain: a 6-month randomized, double-blind, placebo controlled study. Zmitek K, Zmitek J, Rogl Butina M, Pogacnik T. Effects of a combination of water-soluble coenzyme Q10 and collagen on skin parameters and condition: Results of a randomised, placebo-controlled, double-blind study. 2017 Dec 14;12(12):CD009789. 2014 May;44(5):655-70. doi: 10.1007/s40279-013-0137-7. The best vitamins for skin include vitamins C, D, and E. People can get many of these vitamins from their diet or by taking supplements. View abstract. 2014;39(8):874-80. It is made up of amino acids which build our skin, connective tissue, organs, and bones and plays a role in forming the fibroblasts (cell clusters) which allow new cells to grow and replace dead ones. Asserin J, Lati E, Shioya T, Prawitt J. 2012 Jun;20(3):124-30. Mar Drugs. Effects of a nutritional supplement containing collagen peptides on skin elasticity, hydration and wrinkles. 8600 Rockville Pike Nutrition is a key factor influencing skin health and consequently its appearance. View abstract. View abstract. 2022 Jun 17;9:926043. doi: 10.3389/fnut.2022.926043. 2010;35(6):797-804. Br J Nutr. However, it is possible to have too much of a good thing., If calcium is the cause of your collagen-related headache problems, then a simple change in collagen supplement dosage may be in order to reduce the likelihood that your collagen can cause headaches., If you are worried about or already are experiencing headaches from your collagen supplements then it is best to consult a medical professional. 2022 Sep 16;11(18):2869. doi: 10.3390/foods11182869. Kouguchi T, Ohmori T, Shimizu M, et al. These side effects manifest as clinical symptoms best identified by a medical professional. Some other known benefits of collagen peptides include: Consuming collagen peptides are good for you insofar as they may offer a variety of health benefits, from improving joint health to improving your skin. Lim, S. H., Sun, Y., Thiruvallur Madanagopal, T., Rosa, V., & Kang, L. (2018). 2019;11(1). View abstract. Both effects persisted after 12 weeks. WebCollagen is a protein responsible for healthy joints and skin elasticity, or stretchiness. Disclaimer. Possible side effects include: Upset stomach Diarrhea Rashes, or skin reactions Nausea Constipation Heartburn Headache Type 2: This is present primarily in cartilage and can help promote joint health. Asserin J, Lati E, Shioya T, Prawitt J. Can help clear breakouts. Int J Dermatol 2021;60(12):1449-1461. 2022 Dec 17;12(12):1283. doi: 10.3390/metabo12121283. Best collagen supplement for a variety of flavors: Care/Of Collagen Packs. Learn more about collagen vs. biotin. Sci Rep. 2018;8(1):11403. 2020:1-8. Peptides can help ease inflammation, repair damaged skin, and even out skin tone. Use of hyaluronic acid fillers for the treatment of the aging face. However, it is 2020;46(1):156-163. There are also claims that collagen may provide additional health benefits. Ingredients such as dyes and synthetic gelatin found in gummy supplements can be difficult to digest, leading to inflammation of the gut. The researchers theorized that collagen helped stimulate the production of the proteins responsible for muscle growth. WebCollagen is so big and challenging that we cant absorb it as is when we consume it. Methods: Therapeutic Research Faculty 2020. Disclaimer. A pilot study. View abstract. Type 1: This is one of the most abundant types present in the human body and helps support healthy skin. 2006;19(2):92-6. Chemical additives in collagen peptide supplements, such as anti-caking substances and preservatives are common causes of acne flare-ups in those who notice increased breakouts with collagen use. Urinary Hydroxyproline Is Only Suitable As a Biomarker for Acute Intake, Up to 6 hr Postingestion of Collagen Proteins in "Free-Living," Healthy, Active Males. Effects of Collagen Peptides on Recovery Following Eccentric Exercise in Resistance-Trained Males-A Pilot Study. Although rare and typically mild, side effects of collagen peptides on skin often take the form of inflammation and skin breakouts or rashes. Int J Sport Nutr Exerc Metab. government site. Nutr Res 2018;57:97-108.View abstract. Lis DM, Jordan M, Lipuma T, Smith T, Schaal K, Baar K. Collagen and Vitamin C Supplementation Increases Lower Limb Rate of Force Development. pii: E157. There are several potential health benefits that collagen supplements offer. Metabolites. 2017;16(4):520-526. Side Effects of Copper Peptides Overuse of copper peptides in any form of skincare can be bad, but your best line of defense is just not ingesting them. Int Orthop. J Dermatol Sci. What are L-tryptophan supplements? 2008;24(5):1485-96. In studies, collagen peptide supplements have been shown to support skin elasticity 5 and overall hydration 6 . Epub 2022 Jul 23. 2015;18(12):1340-8. The source of the collagen itself should also be a consideration, primarily for those that have a fish or shellfish allergy of any kind. A person should always talk to their doctor before starting any new supplements or increasing the use of any existing supplement. Insulin is an example of a peptide drug, which is composed of 51 amino acids. Our team thoroughly researches and evaluates the recommendations we make on our site. However, scientists have not fully studied all the alleged benefits. The participants skin hydration and elasticity also improved significantly. 2014;27(3):113-9. doi: 10.1159/000355523. Insulin is an example of a peptide drug, which is composed of 51 amino acids. Peptides are also used in Guadanhim LRS, Miot HA, Soares JLM, Silva SAM, Leonardi GR, Lopes RD, Bagatin E. Dermatol Ther (Heidelb). Sports Med. Lee SK, Posthauer ME, Dorner B, Redovian V, Maloney MJ. The oral supplementation with collagen peptides is efficacious to improve hallmarks of skin aging. Beneficial Effects of Oral Supplementation With Ovoderm on Human Skin Physiology: Two Pilot Studies. While we have no reports of ProT Gold users experiencing headaches or migraines after using our collagen products, preliminary research into the topic suggests that there may be a correlation between some collagen supplements and headaches., Whether collagen can cause headaches or not often is dependent on the person taking the supplement, the dosage, the type of collagen, and the supplement quality itself., If you suspect that your supplemental collagen can cause headaches or migraines, then exploring why you have this reaction and how to prevent it will be the first place to start., Before we get into whether collagen can cause headaches, lets look at the overall safety of collagen supplements in general., If youre asking the question: can collagen cause headaches? You are probably also interested in other possible side effects of collagen, and if collagen is a safe supplement to take., Its hard to answer whether collagen can cause headaches and if the supplement itself is safe, simply because the FDA does not regulate most supplements., Since there is such limited regulation of supplements on the market, this leads to immense skepticism regarding how safe they really are and what side effects they cause., The lack of regulation when it comes to supplements versus drugs means that not all supplement companies necessarily have to prove their claims., So, if they are simply trying to sell a product to the consumer, they do not have to have evidence to support whether or not the collagen supplement they are providing actually will benefit the consumer, or whether their supplemental collagen can cause headaches or other issues., Still, the FDA does recognize ingestible collagen as Generally Recognized As Safe (GRAS)., There have been specific collagen supplements that have been recalled by the FDA for safety reasons, which is why it is important to buy from a reputable brand., For instance, our liquid collagen supplement, ProT Gold, is actually recognized as a medical food, which is why it has a nutritional label, not a supplement label., Because of this, ProT Gold is also trusted by over 3,000 medical facilities and used widely for medical nutrition therapy., Something that should be recognized about collagen as a supplement is that it is natural.

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