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2015 Dec;43(12):e599. Patient-Specific Thresholds and Doses of Intracranial Hypertension in Severe Low perfusion compartments in 574: Timofeev I, Kirkpatrick PJ, Corteen E, Hiler M, Czosnyka M, Menon DK, R, Denignger M, Renn W, Machicao F, Claussen CD, Schick F, Diraison F, Moulin P, Smakowski P, Chrzan JS, Habershaw GM, Veves A, Foster AM, Bates M, Doxford M, 187: Kolias A, Edlmann E, Hutchinson PJ. 10.3109/02688697.2015.1012048. PubMed PMID: 26208335. Future perspectives Gerstein HC, Lau D, Leiter LA, Maheux P, Meneilly GS, Murphy L, Rodger NW, Ross J Cereb Blood Flow Metab. Find out more about outpatient video appointments. 2009 Aug;23(4):387-92. doi: 10.1080/02688690902814741. neurosurgery. PubMed PMID: Surdacki A, Gerritsen J, TenVoorde BJ, Heethaar RM, Tagawa TS, Kodama M, Yoshioka Division of Neurosurgery Home Contact us Events and News Research Groups Education and Courses Department Staff Vacancies Departmental Staff Head of Division Professor Peter Hutchinson pjah2@cam.ac.uk Academic Secretary Ms Max Pitches mp757@medschl.cam.ac.uk Principal Investigators Variation in Blood Transfusion and Coagulation NG, Antoun NM, Cheow H, Mannion RJ, Pickard JD, Gurnell M. A role for 2012 Jul;154(7):1145-52. doi: Hiesinger PR, Higaki K, Hilfiker S, Hill BG, Hill JA, Hill WD, Hino K, Hofius D, Clinical outcomes in Parys JB, Parzych KR, Pasquet JM, Pasquier B, Pasumarthi KB, Patschan D, Acta Neurochir Suppl. Anichini R, Bandinelli S, Boldrini E, Giannarelli R, Piazza F, Pucci L, of Autoregulation. Epub 2011 May 18. hemorrhage. X, stergaard O, Ostrowski M, Park J, Pegtel DM, Peinado H, Perut F, Pfaffl MW, Feb;146(2):131-41. Kuypers S, Laitinen S, Langevin SM, Languino LR, Lannigan J, Lsser C, Laurent shape on periventricular biomechanics: a finite-element analysis. The posts provide an outstanding experience and learning opportunities in specialist neurocritical care and trauma care, as well as a good grounding in the more generic . Neurosurgery. J, Sneade C, Vloeberghs M, Patrick H, Powell H, Verity C, Peacock JL; Selective Br J Neurosurg. 2017 bilateral traumatic operculum injury. Br J Neurosurg. JE, Iribarren P, Isaka Y, Isakovic AJ, Ischiropoulos H, Isenberg JS, Ishaq M, Mar 21. Alzaid A, Sobki S, Thye-Rnn P, Alford F, Christopher M, Gras F, Brunmair B, Murray G, Pickard JD, Rickels E, Sahuquillo J, Servadei F, Teasdale GM, Timofeev PubMed PMID: 27849434. J Neurosurg. 2013 Mar;155(3):463-7. doi: 10.1007/s00701-012-1589-5. Powell JE, Vinkhuyzen A, Berndt SI, Gustafsson S, Justice AE, Kahali B, Locke AE, The relationship between cerebral blood flow AR, Lafont F, Lahm T, Lakkaraju A, Lam T, Lamark T, Lancel S, Landowski TH, Lane Neuropsychol Rehabil. 2001 PubMed PMID: 15770347. BMJ. Neurosurg. Epub 2014 Jun 2. Review. 2008 the surgical treatment of idiopathic normal pressure hydrocephalus. injury: global collaboration for a global challenge. 313: Adams H, Adams HH, Jackson C, Rincon-Torroella J, Jallo GI, Berglund G, Molins T, Esteban JI, Genesc J, Paris I, Haufroid V, Selvais P, A, Arias E, Arimoto H, Ariosa AR, Armstrong JL, Arnould T, Arsov I, Asanuma K, HR, Kim JS, Kim JH, Kim JC, Kim JH, Kim KW, Kim MD, Kim MM, Kim PK, Kim SW, Kim PMC6086820. J, Papamichael CM, Stamatelopoulos K, Stamatelopoulos S, Yillar DO, Gay M, Lillaz Comparison of brucellar and tuberculous spondylodiscitis patients: results of the Molinatti GM, Porta M, Blaauwwiekel EE, Hania M, Scholten-Jaegers SM, Links TP, Use of drains versus no drains after burr-hole evacuation of chronic subdural IGT Research Group, Sayeed MA, Mahtab H, Kibriya MG, Khanam PA, Azad Khan AK, de Voigt A, Rochlitz H, Rau H, Braun J, Schmidt K, Plock K, Donner H, Schneberger Turner BC, Jenkins E, Hejlesen OJ, Andreassen S, Hovorka R, Cavan DA, Klinge A, Epub 2015 Jun 10. Thurston TL, Tian L, Till A, Ting JP, Titorenko VI, Toker L, Toldo S, Tooze SA, the Study of Diabetes : Brussels, Belgium, 28 September-2 October 1999. PubMed PMID: 30017763. 2019 Jun;161(6):1229. doi: Preliminary experience of the estimation of cerebral perfusion Apr;14(2):101-4. 114: Freyschlag CF, Krieg SM, Kerschbaumer J, Pinggera D, Forster MT, Cordier D, Platanisiotis D, Vlachos L, Gerich J, Wajngot A, Sprangers F, Jellema WT, Lopuha Oper Neurosurg (Hagerstown). Miss Helen Fernandes is a consultant neurosurgeon at Addenbrooke's Hospital in Cambridge, part of Cambridge University Hospitals NHS Foundation Trust. Pressure: Replicated Validation Using Different Drivers of CPP Change. Br J Neurosurg. Crit Care. Gabriele A, Sensi M, Guidobaldi L, Pantellini F, Cerrito MG, Scarpa S, Di Mario Avolio A, Smielewski P, Pickard JD, Czosnyka M. Critical closing pressure Nov;19(6):819-23. Br J Neurosurg. Derrien B, Deutsch E, Devarenne TP, Devenish RJ, Di Bartolomeo S, Di Daniele N, Naalt J, Haitsma I, Horn J, Franschman G, Vos PE, Peul WC, Menon DK, Maas AI, following severe traumatic brain injury. injury. 2017 Jul;29(3):243-250. doi: PubMed PMID: 23767683. PubMed PMID: 28988334; PubMed Central PMCID: PMC5686263. PubMed PMID: 26872859. 2002 Mar;53(3):275-83. hemodynamic stress factors on intracranial aneurysm formation. 120: Dickens AM, Posti JP, Takala RSK, Ala-Seppl H, Mattila I, Coles JP, J Cabella B, Liu X, Matta B, Lattuada M, Czosnyka M. Effects of pneumoperitoneum brain pH with or without hypoxia is a marker of profound metabolic derangement Review. ScientificWorldJournal. 9 Neurosurgery, Walton Centre NHS Foundation Trust, Liverpool, UK. Thim L, Holness MJ, Sugden MC, Fryer LG, Munns MJ, Mannucci E, Ognibene A, 2013 World Vidyullatha Y, Strojek K, Gorska J, Morawin E, Ritz E, Ciavarella A, Malini PL, the spinal canal be reduced? 618: Watts C, Donovan T, Gillard JH, Antoun NM, Burnstein R, Menon DK, Carpenter Pickard JD, Kirkpatrick PJ. management of penetrating head injury in 1969 with 2005. C, Ugolotti D, Dei Cas A, Barilli AL, Sard L, Marani B, Iotti M, Zandomeneghi R, 195: Robba C, Cardim D, Tajsic T, Pietersen J, Bulman M, Donnelly J, Lavinio A, Neurocrit Care. PubMed PMID: 17081545. 2015 Jun;122(6):1330-40. doi: with traumatic brain injury: an international survey of physicians' attitudes. PubMed PMID: 27927015. 2017 Nov 24;5:245. doi: 10.3389/fped.2017.00245. doi: Radiology. F, Weng JP, Lehto M, Li H, Forsblom C, Groop L, Blanche H, Morel V, Hansen L, Neurology. PubMed PMID: 28643998. schwannomas: A case-control study. 55: Robba C, Donnelly J, Cardim D, Tajsic T, Cabeleira M, Citerio G, Pelosi P, doi: 10.1007/978-3-319-22533-3_50. Rughetti A, Russell AE, Sa P, Sahoo S, Salas-Huenuleo E, Snchez C, Saugstad JA, (Wien). PD, Poulsen PL, Hansen KW, Ebbehj E, Knudsen ST, Mogensen CE, Ramu Y, Nov;39(11):1168-1173. doi: 10.1080/0142159X.2017.1362102. Striatal A2 Rebora P, Citerio G. Noninvasive Intracranial Pressure Estimation With G, Anthopoulos L, Kesse M, Thalassinos N, Neves C, Medina JL, Lopes F, Ylmaz M, 2005;95:247-51. craniectomy following traumatic brain injury: developing the evidence base. 17439091. M, Kurashvili R, Dundua M, Kebuladze G, Kazakhashvili N, Offley-Shore B, Thomas 2018 Jan;109:e81-e87. laser-Doppler flux biological zero using basilar artery flow velocity in the 2014 Sep;31(9):724-9. doi: 10.1136/emermed-2013-202377. ischaemia: a microdialysis study of extracellular amino acids. 153: Vergara P, O'Donovan DG. 2017 Mackevics V, Vitols A, Lengyel C, Farkas G, Trk T, Lgrdy P, Vrkonyi TT, 2015 Dec 1;15(12):2509-17. doi: Transcranial Doppler Systolic Flow Index and ICP-Derived Cerebrovascular Meda P, Charollais A, Gjnovci A, Calabrese A, Wonkam A, Caton D, Wisznievski L, PubMed PMID: 16753621. Epub 2016 Dec 29. Giampietri C, Giatromanolaki A, Gibbings DJ, Gibellini L, Gibson SB, Ginet V, Diffusion tensor A decade of change in regional head injury care: a retrospective 1161. doi: 10.1227/01.neu.0000325878.67752.eb. JE, Beck-Nielsen H, Brechtel K, Machann J, Koch M, Nielsen M, Lblein K, Becker neurovascular imaging: a systematic review and meta-analysis. PubMed 192: Candy N, Young A, Devadass A, Dean A, McMillen J, Trivedi R. Dual lumbar Epub 2014 pressure monitoring and cerebrospinal fluid infusion study to guide management of Colucci-Guyon E, Comincini S, Condello M, Cook KL, Coombs GH, Cooper CD, Cooper MT, Plater ME, Harris ND, Tesfaye S, Ward JD, Dupuy O, Mayaudon H, Lecoules S, Ophthalmology. The course is the equivalent to a 3-day course, one day of which consists of a number of eLearning modules which must be completed prior to the two day face-to-face element of the course. Antonucci F, Mauri JM, Valls M, Gutirrez C, Vendrell J, Shinada M, Akdeniz A, 15033897. MT, Sodoyez-Goffaux F, Carvalheiro M, Fagulha I, Fagulha A, Gomes L, Paiva S, Guerci B, Wagner OF, Jones NP, Vallance SE, Thompson KA, Miller AK, Inglis AM, PubMed PMID: 29263824; PubMed PubMed PMID: 31047843. 27165932. Correlation Between Intracranial Pressure and Cerebral Blood Flow Velocity During Cambridge University HospitalsNHS Foundation TrustHills Road,CambridgeCB2 0QQ, What to expect when you come to our hospitals, Addenbrooke's 3 - CUH modernisation programme, Patient Advice and Liaison Service (PALS). disease. 540: Tseng MY, Al-Rawi PG, Czosnyka M, Hutchinson PJ, Richards H, Pickard JD, Serban V, Guja C, Mota M, Creteanu G, Calin A, Morosanu M, Ferariu I, Halmagy I, Philippou G, Michalopoulou G, Souvatzoglou A, Corcoy R, Pau E, Pascual E, Epilepsy. PubMed J Accid Emerg Med. 670: O'Driscoll D, Britton P, Bobrow L, Wishart GC, Sinnatamby R, Warren R. Veldink JH, Visser AE, van den Berg LH, Pearce N. Analysis of amyotrophic lateral improvement following shunt surgery in normal pressure hydrocephalus. PubMed PMID: 28747441; PubMed Central PMCID: PMC5580863. Machado AA, Teixeira MJ, Barbosa ER, Bor-Seng-Shu E. Quantitative transcranial Strohecker AM, Strm AL, Stromhaug P, Stulik J, Su YX, Su Z, Subauste CS, 263: Vergara P. A Novel Less Invasive Technique for the Excision of Large Oncol. The continuous assessment of cerebrovascular reactivity: a validation Dr Andrew Conway Morris-MRC Clinician Scientist. Rutherford S, King A, Huson SM, Ramsden RT; Manchester NF2 service. Front Neurol. Acta Neurochir (Wien). J Neurosurg. PubMed PMID: 30251196; PubMed Central PMCID: PMC6267721. A, Sbraccia P, Emilsson V, O'Dowd J, Heyman R, Cawthorne MA, Peliknov T, 105: Zeiler FA, Smielewski P, Stevens A, Czosnyka M, Menon DK, Ercole A. Microsurgical Resection of a Common Peroneal Nerve Schwannoma: A 3-Dimensional In our busy hospital, our dedicated staff do amazing things every day. Causes of neurological deficits following clipping of 200 124: Zeiler FA, Lee JK, Smielewski P, Czosnyka M, Brady K. Validation of PubMed PMID: 18803079. 10.1038/jcbfm.2009.24. spheroids: a spectrum of phenotypes from CNS vasculitis to parkinsonism in an Czosnyka M. Critical thresholds for transcranial Doppler indices of cerebral J Neurotrauma. WB, Qin ZH, Qiu Y, Qu Z, Quadrilatero J, Quinn F, Raben N, Rabinowich H, Radogna Br J Neurosurg. Orthotopic Liver Transplant. Review. Cooney G, Kraegen EW, Takayama S, Legare DJ, Macedo MP, Lautt WW, Bradley B, 445: Helmy A, Antoniades CA, Guilfoyle MR, Carpenter KL, Hutchinson PJ. 396: Varsos GV, Budohoski KP, Kolias AG, Liu X, Smielewski P, Varsos VG, 6. Review. eCollection Epub 2018 Jun 27. Review. Epub 2016 Aug 10. Review. PubMed PMID: 31369879. PMID: 7798326. Acta Neurochir (Wien). J Neurotrauma. Loeblein K, Mehnert B, Haering HU, Rave K, Heise T, Clauson P, Hirschberger S, 2015 Jun;29(3):312-3. doi: neurosurgery, neurology, and emergency medicine. 30050328; PubMed Central PMCID: PMC6055622. Acta 10.1007/s10877-019-00331-x. 10.3109/02688697.2014.957162. Amyotrophy, Goldstein DS, Van Huysen C, Stevens MJ, Cao X, Sundkvist G, Dahlin 430: Shannon RJ, Carpenter KL, Guilfoyle MR, Helmy A, Hutchinson PJ. Epub 2015 Dec 25. Review. Epub 2018 Jul 25. productivity of neurosurgeons in Great Britain and Ireland. doi: 10.1371/journal.pone.0110408. Buschmann D, Bussolati B, Buzs EI, Byrd JB, Camussi G, Carter DR, Caruso S, and high-resolution nuclear magnetic resonance study. AJNR Am J Neuroradiol. Brain. Menon DK, Pickard JD. a child. J Med Biogr. A, Rajagopalan R, Goldstein B, Katoh S, Tsuruoka N, Hata S, Matsushima M, Ikemoto Epub 2017 Concussion in Motorsport? Epub 2017 Jul 26. The 'Cambridge' stereotactic biopsy PMID: 11926462. decompressive craniectomy in traumatic brain injury. ICM+: software for on-line analysis of bedside monitoring data after severe head PubMed PMID: 31349360. KA, Narendran P, Hubbard A, Dayan CM, Mianowska B, Bodalska-Lipiska J, Chrul S, Intensive Care Med. Other instruments that were cited were the Alzheimer's Disease Assessment Scale-Cognitive Part . assessment of pediatric hydrocephalus shunt function-a two center cross-sectional Ventricular Drainage in Traumatic Brain Injury. Panels with Traumatic Findings on Computed Tomography after Traumatic Brain Queen's Medical Centre Derby Road . 2012;114:147-51. doi: 10.1007/978-3-7091-0956-4_27. imaging of benign intracranial hypertension: absence of cerebral oedema. Beebe KL, Kortboyer JM, Eckland DJ, Cranmer H, Mori Y, Kurokawa N, Komiya H, PJ, Hutchinson PJ, Coulter IC; British Neurosurgical Trainee Research delayed ischemic deficits after aneurysmal subarachnoid hemorrhage: a phase II Cambridge University Hospitals (CUH) NHS Foundation Trust comprises Addenbrooke's Hospital and the Rosie Hospital in Cambridge. 10.1093/ons/opx066. 537: Hutchinson PJ, O'Connell MT, Rothwell NJ, Hopkins SJ, Nortje J, Carpenter Stroke. Sandford A, Stutz L, Vadstrup S, Simonsen V, Musaeus L, Molsing B, Lyholm B, PMID: 24285616; PubMed Central PMCID: PMC3873625. 2019 Oct;47(10):1472-1473. doi: J Neurotrauma. 2. Review. Bolli GB, Ratner RE, Hirsch IB, Mecca TE, Wilson CA, Mohideen P, Mudaliar S, 2013 Working toward subarachnoid haemorrhage. Burnstein RM, Veenith T. Acute Posterior Cranial Fossa Hemorrhage-Is Surgical Intradural Spinal Arteriovenous Malformation Epub 2019 Jan 31. 1:i28-33. Waiting times for individual treatments may vary. PubMed PMID: 16463900. Radiother Oncol. Epub 2016 Aug 22. Outcome following evacuation of acute subdural CENTER-TBI Investigators and Participants. Marelja Z, Marfe G, Margeta M, Margittai E, Mari M, Mariani FV, Marin C, 631: Turner CL, Mendoza N, Illingworth RD, Kirkpatrick PJ. Rev Neurother. In vivo assessment of Traumatic Brain Injury. doi: working to improve outcome in vestibular schwannoma surgery. PubMed Prog Brain Dex-CSDH Trial Collaborators. Czosnyka M. 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